Prior to the application, large quantities of liquid is consumed. Traditionally the tribes use cassava or massato (a fermented yucca or banana gruel). Occasionally they will use diluted papaya or other juice, and as an absolute backup, about 500ml of water. The immediate effects of kambo are intense but short lived, usually lasting no more than 30 to 40 minutes. They may include a rise in temperature, sweating, shivers, and dizziness as the heart rate increases. Blood pressure may also rise or fall dramatically. Many people report a tingling or burning sensation similar to electricity that starts at the points of application and spreads throughout the body. Some may even feel a heightened awareness or a drunken high feeling.
Nausea is to be expected during Kambo as physical purging (either by vomiting, sweating, or defecating or a combo of all three), emotional purging, or mental purging take place. Other effects may include pressure in the head and neck, stomach pain, inflammation of the throat, dry mouth, blurred vision, difficulty moving, numbness, and swollen lips and tongue.
Kambo treatments involve a deep physical and energetic cleansing of the body that can be used to address a number of conditions ranging from depression, CFS, autoimmune, migraines, laziness, chronic pain, removal of infections and/or toxins, and other issues.